Welcome to the Hampton Inn by Hilton Owensboro South

LOCATION - Our award winning Hampton Inn by Hilton Owensboro-South is conveniently located for all thoroughfares in Owensboro; including the Owensboro Convention Center, Owensboro-Daviess County Airport, Smothers Park, and the industry that is sprinkled throughout the city. We are within walking distance to the Adkisson Greenbelt Park, which is a 15-mile trail encircles the city and links neighborhoods, business districts, parks, and schools. You will find Owensboro's signature Bourbon, Bluegrass and Bar-B-Q within a few miles.

OUR HOTEL - Our top-ranked, locally-owned Hampton Inn by Hilton Owensboro-South offers 86 smoke-free guest rooms, including 8 suites. Our spacious guest rooms feature complimentary Internet, flat-screen TVs with extended HD channel selections, in-room coffee makers, hair dryers, microwaves, refrigerators, iron & ironing boards, and voice mail. Other amenities available to guests include complimentary digital newspapers, local calls, and a delicious hot breakfast. All of these are to provide all the comforts expected by today's traveler. We also offer connecting rooms, cribs, on-site guest laundry, and dry cleaning. At our 100% non-smoking hotel, you'll find additional amenities such as a 24-hour business center, on-site fitness center, outdoor pool and patios. We also offer complimentary coffee, tea & hot chocolate served 24 hours in our lobby. You'll be Happy, we guarantee it. That's our 100% Hampton Guarantee!

Earn Points and Miles by staying at our Hampton Inn by Hilton Owensboro hotel as a member of the Hilton Honors® Program.


86 Guestrooms & Suites

  • Flat screen TVs with extended HD channels
  • Microwave and Refrigerator
  • Coffee Makers
  • Hair Dryer
  • Iron & Ironing Board
  • Voice Mail
  • King Bed or Queen Beds
  • ADA Accessible Rooms available
  • Connecting Rooms, Cribs and Rollaway Beds available upon request


Hotel Services & Amenities

  • Complimentary WiFi
  • Complimentary Local Calls
  • Complimentary Parking
  • Hot Breakfast Included
  • Check-in: 3:00 PM | Check-out: 11:00 AM
  • Business Center
  • Outdoor Pool & Patio
  • Fitness Room
  • Non-smoking



Dining out is a must! You'll find dozens of restaurants to choose from, no matter what you're craving. Dining in Owensboro will please any palette. From steaks, oysters and pizza to Greek, Italian, Mexican and delicious American food, you'll find the perfect dining option for your taste and budget.



Owensboro is home to unique attractions, special events and more than 20 annual festivals. From free to budget-friendly, here in Owensboro you'll be able to enjoy National & State Parks, Annual Festivals and fun attractions.
Come and enjoy everything Owensboro has to offer!



Centrally located among numerous midwestern cities, Owensboro’s hospitality, attractions, world class convention center and wide variety of original culinary options make it a winning choice for conventions and meetings of any kind. We invite you to visit Owensboro and explore everything we have to offer.


Owensboro Calendar of Events

Guest Reviews by TripAdvisor

Our location

Located at 615 Salem Dr

Explore Owensboro, KY

  1. Downtown Owensboro
  2. Smothers Park, Riverpark Center, International Bluegrass Music Museum
  3. Owensboro Convention Center
  4. Town Square Mall
  5. Owensboro-Daviess County Regional Airport
  6. Moonlight Bar-B-Q
  7. Owensboro Country Club
  8. YMCA
  9. Hillcrest Golf Court
  10. The Next Level



Hampton Inn by Hilton Owensboro South

615 Salem Drive - Owensboro, KY 42303
Phone: +1 270.926.2006 | Fax: +1 270.684.0330

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